Use of episcleral cyclosporine implants in dogs with keratoconjunctivitis sicca: pilot study
نویسندگان
چکیده
منابع مشابه
Tear ferning in normal dogs and dogs with keratoconjunctivitis sicca
This study evaluates tear ferning as an ancillary technique for the evaluation of the canine tear film in normal eyes and eyes affected by keratoconjunctivitis sicca (KCS). Thirty dogs with KCS and 50 control dogs with normal tear film were evaluated with a full ophthalmoscopic examination and a Schirmer tear test type 1 (STT) determined before tear samples were obtained from the medial canthus...
متن کاملCyclosporine-loaded delivery system for the treatment of keratoconjunctivitis sicca: a pilot study
Objetivo: Este trabalho objetivou o desenvolvimento de um sistema mucoadesivo de liberação de ciclosporina A (CsA) para o tratamento de ceratoconjuntivite seca (CCS). Métodos: O sistema mucoadesivo foi preparado na forma de filme utilizando o polímero quitosana e CsA (25%p/v). Foram administrados no saco conjuntival do olho direito de coelhos normais (n=6) e a aferição da produção de lágrimas f...
متن کاملEffect of cyclosporine on conjunctival mucin in a canine keratoconjunctivitis sicca model.
PURPOSE To test the hypothesis that beneficial effects of Cyclosporin A (CsA; Sandimmune; Sandoz, Basel, Switzerland) in treating keratoconjunctivitis sicca (KCS) include an effect on the mucin-producing conjunctival goblet cells independent of CsA's effect on lacrimation. METHODS Keratoconjunctivitis sicca was induced bilaterally in six dogs after removal of orbital and nictitans lacrimal gl...
متن کاملImmunohistochemical evaluation of lymphocyte populations in the nictitans glands of normal dogs and dogs with keratoconjunctivitis sicca
Idiopathic canine keratoconjunctivitis sicca (iKCS) is a common condition of the canine eye involving a deficiency in aqueous tear production which is commonly held to have an immune-mediated, as most probably an autoimmune aetiopathogenesis. Yet to date no direct evaluation has been made of the inflammatory cell populations in the lacrimal tissue of dogs with iKCS. Here we sought to quantify T...
متن کاملKeratoconjunctivitis sicca due to sarcoidosis.
SARCOIDOSIS is well recognized as a cause of swelling of the lacrimal glands and enters into the differential diagnosis of tumours of this region (DukeElder, 1952). Such swellings may be followed, in some cases, by a form of keratoconjunctivitis sicca (Ainslie and James, 1956; Gruber, 1956). The association of systemic sarcoidosis with keratoconjunctivitis sicca in the absence of swelling of th...
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ژورنال
عنوان ژورنال: Veterinary Ophthalmology
سال: 2014
ISSN: 1463-5216
DOI: 10.1111/vop.12173